วันพุธที่ 19 ตุลาคม พ.ศ. 2554

Malaria vaccine could save millions of children's lives

Researchers

'at dawn' of a vaccine after the large-scale trial in Africa showed that the risk of malaria halved

lives million children could be saved with a new vaccine can halve the risk of malaria in the first large-scale trials in seven African countries.

The results of the long-awaited vaccine against malaria the biggest in history, involving 15 460 infants and young children who could show massively reduce the devastating impact of the dreaded disease. Malaria takes nearly 800,000 lives a year - mostly children under five years. Much more damaging.

The vaccine was in development for two decades - the idea of ??scientists in the UK, a pharmaceutical company GlaxoSmithKline, which has promised to sell no more than a fraction of the cost, the surplus being reinvested in new research on tropical diseases.

"These data lead us to the verge of having the vaccine against malaria in the world, first with the potential to significantly improve the prospects of children living in areas of endemic in Africa, "said CEO Andrew Witty of GSK.

"The addition of a vaccine to control interventions against malaria in place, such as mosquito nets and insecticides, may help prevent millions of cases of this debilitating disease. It could also reduce the burden of hospital services, the release of much needed beds for the treatment of other patients who often live in remote villages with little or no access to health services. "

ingenious told the Guardian he was delighted by the scientists, who were regarded by many of their peers to attempt the impossible when we started working on a vaccine 25 years ago. "When the team was first shown the data, many of them began to cry," he said. "It was the thrill of what they had accomplished the first -.. vaccine against a parasitic form of the infection were overwhelmed says something about the amount of heart that has gone into this project. "

In a sign that the weight of expectation surrounding this vaccine, still known only as RTS, S, the results were announced at a forum on Malaria in Seattle named Bill and Melinda Gates, assisted by the World Health Organization Director General, Dr Margaret Chan, Secretary for Development and the United Kingdom, Andrew Mitchell. The results were published online at the same time by the New England Journal of Medicine.

Mitchell said the vaccine "offers real hope for the future", adding: "A vaccine effective, sustainable and profitable to make a significant contribution to the fight against malaria ... but we should not lose sight of the fact that over 2000 people die of malaria every day and need help now focus. Britain is kept on driving by this terrible loss of life through prevention and treatment of malaria with the tools we have now and the fight against resistance. "

Questions remain about the price of the vaccine and, if donors are willing to pay. Dr. Regina Rabinovich, the Bill and Melinda Gates declined to say whether he would fund it, saying he wants to see the final data on the effectiveness, durability and safety. "Would you rather see a vaccine 100% effective? By the way, "he told a news conference.

ingenious said urges all those involved in vaccine production to reduce costs to the bone. "We are totally committed to what is as small as possible," he said.


Christopher Elias, president and CEO of PATH, a nonprofit organization that helped fund the study, with the help of the Gates Foundation, said the high quality science is moving in the fight against malaria.


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