An interview with the backyard brain co-founder Tim Marzullo
The first of my two new features of the Society for Neuroscience annual meeting is online. This is a mini-symposium called low-cost student in neuroscience amateur, high school, undergraduate, and public, held on Saturday, November 12.
The symposium was chaired by Tim Marzullo, co-founder of the brain in the back yard, a young company that manufactures and distributes equipment accessible to students of all ages neuroscience. Its latest product, they showed at the conference allows students to use optogenetics, a technical state of the art in which neuronal activity can be animal behavior and manipulated with laser light.
my article, Do-It-Yourself Neuroscience is online at the website of the Dana Foundation. Tim interviewed for the piece and the transcript is below. Ewen Callaway also covered optogenetics to play
Nature
Why and Greg's brain to the backyard?
I had to go to college and get a doctorate in neuroscience. I am crazy enough to want to be a professional neuroscientist, but for all researchers, there are thousands of others who have a natural curiosity about the brain. If astronomy were the neurosciences, you need a PhD to look through a telescope. It is completely ridiculous. The technology of the recording of action potentials is 90 years and there is no technological barrier for which you can not put in the schools. We had to build a small amplifier and effectively distributed. I come from a family of teachers, and I'm kind of a gearbox, so the backyard brain to combine my love of Neuroscience, education and building things.
GM needs, so we are limited in our models. We have a partner [Stefan Pulver] University of Cambridge and Cornell has made these transgenic Drosophila channelrhodopsin expressed in all cholinergic neurons. Using 3D printing technology, we designed, printed and assembled a handful to the position of our electrodes. Then we took a microscope off-the-shelf [brain court co-founder] Greg invented the last component required - a control circuit with LED.
using an iPad can precisely deliver pulses of blue light at any interval you want to stimulate the preparation. In the fruit fly larvae, CHR2 is expressed in cholinergic neurons make muscles contract when stimulated. Look through the microscope and see larvae crawling on the substrate, which glow with a blue light on them and the contract 
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